Chemistry
1. Combinatorial compound library synthesis
2. High-throughput Screening
3. Chemical probe synthesis
Gao, Yu (Tom) yugao@uic.edu
Assistant Professor, CV
Department of Pharmaceutical Science
University of Illinois Cancer Center
B.S. (2008) Peking University, School of Pharmaceutical Sciences
Ph.D. (2014) The Scripps Research Institute (Dr. Thomas Kodadek)
Post-doc (2018) The Scripps Resaerch Institute (Dr. John Yates III)
Shao, Xinhao xshao8@uic.edu
Graduate student, CV
Department of Pharmaceutical Science
B. Eng (2016) Heilongjiang University, pharmaceutical engineering
M.S. (2018) Bioengineering, Illinois Institute of Technology
Never limits challenges, challenge limits.
Zhang, Ziwei zzhan60@uic.edu
Graduate student, CV
Department of Pharmaceutical Science
B.S. (2015) Peking University, Schoool of Pharmaceutical Sciences
M.S. (2017) Peking University, Schoool of Pharmaceutical Sciences (Dr. Demin Zhou)
May the force be with you
Hollas, Michael mhollas@uic.edu
Post-doc, CV
Department of Pharmaceutical Science
MChem (2011) St. Johns College, University of Oxford
Ph.D. (2017) University of Manchester
i'm struggling with the funny description...
Ma, Xiuyuan mxyuan126@gmail.com
Post-doc, CV
Department of Pharmaceutical Science
B.S. (2013) Nanjing University, Department of Chemistry and Chemical Engineering
Ph.D. (2019) Rutgers University (Dr. Elena Galoppini)
A lover of life.
Abdeljaber, Ameer aabdel38@uic.edu
Undergraduate Student, CV
Department of Pharmaceutical Science
Undergraduate at University of Illinois at Chicago (2017-)
@Gao lab since 2019.7
Mass spectrometry-based Proteomics and Metabolomics are power tools to survey the biological system. When combined with chemical enrichment and chemical labeling, these tools are even more powerful. Our research interests focuses on single-cell proteomics and highly sensitive protein detection method.
Our main interest in Chemical Biology is to create chemical tools to investigate and manipulate protein-protein interaction. Particularly, we are interested in developing activity-based probes and chemical crosslinkers to elucidate protein-protein interactions.
Combinatorial Chemistry allows us to synthesize millions of compounds in days. Within these millions of compounds, many of them are potent binders and inhibitors. We collaborate with UICentre to create methods to identify bioactive compounds efficiently.
Bioinformatics is the key to process the massive data generated by modern mass spectrometers. Our interest in bioinformatics is to develop powerful tools to convert Big Data to Knowledge. We have been working on multi-omics data analysis, deep proteomics data analysis and metabolomics data quantitation.
1. Combinatorial compound library synthesis
2. High-throughput Screening
3. Chemical probe synthesis
1. Glycoproteomics
2. Phosphoproteomics
3. Quantitative analysis
1. Multi-omics data integration
2. Statistical analysis
3. Software development
All the software provided here are developed by me and free to use for research purposes. If you used my tools for you publication, please include proper citations.
For any other use, please contact bathyg(at)gmail.com
Are you interested in collaborating? Have any suggestions?
Drop us an e-mail or visit our lab at University of Illinois at Chicago
Also, if you find any bug from our tools, please let us know!
1. Post-doc level researchers in the field of (a) organic chemistry (b) chemical biology (c) proteomics (d) bioinformatics (e) other related areas. Details
2. Graduate students with B.S. or B.A. in STEM.
3. Technicians, both hourly paid and long-term position. Will be in charge of mass spectrometry and other common lab duty.
4. Visiting Scholars, must be from related field, willing to learn new things.
5. Talented part-time graduate/undergraduate students
To apply, submit your CV here.
Feel free to stop by:
833 S Wood St. 5th Floor, 552
Chicago, Illinois, 60612
United States